Atorcam-40 Tablets

(Atorvastatin 40mg Tablets Manufacturers Suppliers)

Trumac Healthcare is one of the leading Atorvastatin 40mg Tablets Manufacturers Suppliers all over India.

Atorvastatin 40mg Tablets Manufacturers Suppliers

Composition

Each film coated film tablet contains:

Atorvastatin I.P 40mg

MRP

155/- per 10 tab

PACKING

10 x 10 (Alu Alu)

ATORVASTATIN

Atorvastatin is used in the treatment of high cholesterol and high triglycerides.

Atorvastatin is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lowers "bad" cholesterol (LDL), triglycerides and raises "good" cholesterol (HDL).

ATORVASTATIN

After oral administration, Atorvastatin is rapidly absorbed, with peak serum concentrations reaching within 1 to 2 hours. Extent of absorption increases in proportion to Atorvastatin dose. The absolute bioavailability of Atorvastatin is approximately 14% and the systemic availability of HMG-CoA reductase inhibitory activity is approximately 30%. Mean volume of distribution is approximately 381 liters. Atorvastatin is ≥ 98% bound to plasma proteins. Atorvastatin is extensively metabolized to ortho-and para hydroxylated derivatives and various beta-oxidation products. Approximately 70% of circulatory inhibitory activity for HMG-CoA reductase is attributed to active metabolites. Atorvastatin and its metabolites are eliminated primarily in bile following hepatic and/or extrahepatic metabolism; however the drug does not appear to undergo enterohepatic recirculation.

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