Moxirut-400 Tablets

(Moxifloxacin Tablets Manufacturers Suppliers)

Trumac Healthcare is one of the leading Moxifloxacin Tablets Manufacturers Suppliers all over India.

Moxifloxacin Tablets Manufacturers Suppliers


Each Film Coated Tablet Contains:
Moxifloxacin I.P 400mg


120/- per 5 tab


20 x 5 (Blister)


Moxifloxacin is used in the treatment of bacterial infections. It is also used in infections of urinary tract, tonsils, sinus, nose, throat, female genital organ, skin and soft tissues, windpipe and lungs (pneumonia).


Moxifloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial DNA, thereby inhibiting cell replication.



Moxifloxacin is a recently developed fluoroquinolone antibiotic. It is rapidly absorbed following oral administration, reaching a mean peak drug plasma concentration (C(max)) of approximately 3.56 mg/l within 2 h after a 400 mg dose. The rate and extent of absorption are not significantly affected by food or elevated gastric pH. Moxifloxacin binds weakly to plasma proteins and penetrates well into most tissue and fluid compartments, with generally higher drug concentrations in tissue and fluid compartments than those observed in plasma. Moxifloxacin is metabolized to an N-sulfate conjugate and an acyl glucuronide in humans. The N-sulfate and the unchanged moxifloxacin are detected in plasma, urine and feces. The acyl-glucuronide is detected in plasma and urine, but not in feces. The plasma elimination half-life ranges from 8.2-15.1 h in healthy individuals. The urinary excretion of the unchanged drug accounts for 19-22% of the given dose. Neither renal nor hepatic impairment significantly affect the pharmacokinetics of moxifloxacin.


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