Vonoprazan HP Kit PCD Franchise in India: 2026 Guide
Vonoprazan HP Kit PCD Franchise & Distributorship in India — Vonozest-Trio (Vonoprazan 20 mg + Clarithromycin 500 mg + Amoxycillin 500 mg) 14 x 1 combikit by Trumac Healthcare
The vonoprazan HP kit is the fastest-moving product in Indian gastroenterology this year. Gastroenterologists and physicians are switching H. pylori patients from the familiar pantoprazole, esomeprazole and rabeprazole kits to vonoprazan-based triple therapy, and chemists are being asked for “the vonoprazan HP kit” by name. For PCD franchise partners and distributors this is a chance to enter a growing segment early, with a 14-day course product that is prescribed, dispensed and completed as one box. This guide explains how the vonoprazan HP kit PCD franchise works with Trumac Healthcare.
View Vonozest-Trio Vonoprazan HP Kit – product details 📱 WhatsApp for franchise rates
Why vonoprazan HP kits are replacing PPI HP kits
- Stronger, faster acid suppression. Vonoprazan is a potassium-competitive acid blocker (P-CAB). It does not need acid activation, so it suppresses acid fully from the first dose, while PPIs take several days to reach full effect.
- Not affected by CYP2C19 genotype. Many Indian patients are rapid CYP2C19 metabolisers, which reduces the effect of PPIs. Vonoprazan is metabolised mainly by CYP3A4, so its effect is more predictable.
- Better eradication in trials. In large clinical trials, vonoprazan-based triple therapy achieved higher H. pylori eradication rates than PPI-based triple therapy, including against clarithromycin-resistant strains.
- Doctor and patient demand. Failed PPI-kit courses are common, and doctors increasingly start with — or switch to — a vonoprazan HP kit. That creates steady prescription pull for a kit that is always sold as a complete course.
About Vonozest-Trio – Trumac Healthcare’s vonoprazan HP kit
| Composition (per day pack) | Vonoprazan 20 mg (2 tablets) + Clarithromycin 500 mg (2 tablets) + Amoxycillin 500 mg (4 capsules) |
|---|---|
| Regimen | Vonoprazan 20 mg BD + Clarithromycin 500 mg BD + Amoxycillin 1 g BD, for 14 days |
| Pack | 14 x 1 combikit – fourteen one-day packs laid out AM / PM; one box = full course |
| Storage | Below 30 °C, dry, protected from light – no cold chain needed |
Because each box holds the complete 14-day course, the chemist dispenses once and the patient is far more likely to finish therapy — the single biggest factor in eradication success. Full clinical information is on the Vonozest-Trio vonoprazan HP kit page.
What franchise partners and distributors get
- Monopoly rights for the Vonozest range at district or state level.
- Competitive net rates with healthy PTR/PTS margins on a full-course, high-value kit.
- Visual aids and literature explaining P-CAB vs PPI therapy for doctor detailing.
- A complete acid-peptic basket: Vonoprazan 20 mg tablet (Vonozest) for GERD and ulcer maintenance, and Tegoprazan 50 mg tablet (Tegozest-50), the newer P-CAB.
- Dispatch within 48 hours of payment realisation, with batch Certificates of Analysis.
Who should take a vonoprazan HP kit franchise
- PCD franchise owners building a gastro division
- Medical representatives with gastroenterologist, physician and surgeon contacts
- Distributors supplying retail chemists and hospital pharmacies
- Endoscopy and gastro clinics with an attached licensed pharmacy
Documents and investment
You need a valid drug licence (retail or wholesale) and GST registration. No cold chain is required. Most partners start with an opening order of the HP kit together with the vonoprazan 20 mg tablet, and scale up as prescriptions build; share your expected monthly volume and we will suggest an opening quantity.
Prescribing and compliance notes
The vonoprazan HP kit is a prescription-only medicine for H. pylori eradication in adults. It is contraindicated in patients allergic to penicillins, macrolides or vonoprazan, and clarithromycin interacts with many drugs metabolised by CYP3A4. A test of cure (urea breath test or stool antigen) is usually done at least four weeks after the course. Promotion must stay within the approved indications on the label, and sales must be against a valid prescription.
How to start in four steps
- Send your district or state, drug licence and GST details on WhatsApp at +91 90416 77932.
- We confirm monopoly availability and share net rates for Vonozest-Trio and the Vonozest range.
- Sign the franchise agreement and place the opening order.
- Receive dispatch with visual aids and literature, and start detailing.
Frequently asked questions
What is a vonoprazan HP kit?
A vonoprazan HP kit is a co-packaged triple therapy for Helicobacter pylori eradication containing vonoprazan 20 mg, clarithromycin 500 mg and amoxycillin 500 mg, laid out as one-day packs for a 14-day course. Trumac Healthcare’s vonoprazan HP kit is Vonozest-Trio.
How is a vonoprazan HP kit different from a PPI HP kit?
PPI kits use pantoprazole, esomeprazole, rabeprazole or lansoprazole. Vonoprazan is a potassium-competitive acid blocker that gives strong acid suppression from the first dose and is not affected by CYP2C19 metaboliser status, and vonoprazan-based triple therapy has shown higher eradication rates than PPI-based triple therapy in clinical trials.
Is Vonozest-Trio vonoprazan HP kit available for PCD franchise?
Yes. Vonozest-Trio is available on monopoly PCD pharma franchise and distributorship basis across India, with monopoly rights at district or state level. A valid drug licence and GST registration are required.
What is in one box of Vonozest-Trio?
One box is a 14 x 1 combikit: fourteen one-day packs, each with 2 vonoprazan 20 mg tablets, 2 clarithromycin 500 mg tablets and 4 amoxycillin 500 mg capsules, arranged AM and PM. One box covers the full 14-day course.
Do you offer third party manufacturing of vonoprazan HP kits?
Yes. Third party and contract manufacturing of vonoprazan HP kits under your own brand is available subject to minimum order quantity, valid licences and artwork approval. Contact +91 90416 77932.
Book your vonoprazan HP kit franchise territory
Monopoly districts are allotted first-come. Call or WhatsApp +91 90416 77932 for net rates on Vonozest-Trio and the Vonozest range.