Aminowise-L IV Infusion
L-Alanyl L-Glutamine 20% IV Solution — Parenteral Glutamine Supplementation
| Composition | L-Alanyl L-Glutamine 20% Solution |
|---|---|
| Dosage Form | IV Infusion (Glass Bottle) |
| Pack Type | Glass Bottle |
| Pack Size | 50 ml Glass Bottle |
| MRP | ₹ 1599 |
| Therapy | Infusion + G.P. — Parenteral Dipeptide Glutamine Supplement |
| Storage | Store below 25 °C, protected from light. Do not freeze. Once opened, use immediately. |
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About Aminowise-L IV Infusion
Aminowise-L IV is a 50 ml parenteral solution containing L-Alanyl L-Glutamine 20% — a stable dipeptide form of glutamine designed to overcome glutamine’s poor solubility and instability in conventional IV fluids. Glutamine is the most abundant amino acid in plasma and skeletal muscle, but becomes conditionally essential during critical illness, sepsis, major surgery and burns.
Parenteral L-Alanyl L-Glutamine restores plasma glutamine concentrations in catabolic patients, supporting gut mucosal integrity, immune cell function, antioxidant glutathione synthesis and skeletal muscle protein balance. It is used as part of total parenteral nutrition (TPN) or as an adjunct in ICU and post-operative care.
Aminowise-L IV is manufactured by Trumac Healthcare under WHO-GMP injectable-grade conditions. Available for monopoly-based PCD pharma franchise and third-party manufacturing — a critical-care and hospital-formulary SKU.
Indications
- Glutamine supplementation in critically ill patients (ICU, sepsis, major trauma)
- Adjunct to total parenteral nutrition (TPN) in catabolic states
- Pre- and post-operative nutritional support
- Severe burns and major surgical recovery
- Inflammatory bowel disease and short bowel syndrome (specialist use)
Mechanism of Action
L-Alanyl L-Glutamine is hydrolysed in plasma and tissues by aminopeptidases to release free glutamine and alanine. Glutamine fuels enterocytes and immune cells, supports glutathione synthesis (the principal intracellular antioxidant), and serves as a nitrogen donor for nucleotide and amino-sugar synthesis. The dipeptide form allows safe high-dose IV delivery that free glutamine cannot achieve.
Dosage & Administration
Adult dose is calculated by body weight (typically 0.3–0.4 g amino acid/kg/day) and administered by slow IV infusion mixed with a carrier amino-acid solution, under medical supervision. Strictly hospital use.
Side Effects
Generally well tolerated. Possible infusion-related nausea or chills if infused too rapidly. Phlebitis at IV site. Rare: hypersensitivity reactions, alterations in serum ammonia.
Contraindications & Precautions
Hypersensitivity to glutamine or alanine. Severe hepatic insufficiency with encephalopathy. Severe renal impairment without dialysis. Inborn errors of amino acid metabolism. Severe metabolic acidosis.
Storage
Store below 25 °C, protected from light. Do not freeze. Once opened, use immediately.
Aminowise-L IV Infusion is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Aminowise-L IV used for?
Aminowise-L IV is a parenteral solution of L-Alanyl L-Glutamine 20% used to supply conditionally essential glutamine to critically ill, post-operative, burn and TPN patients — supporting gut, immune and muscle function.
How is Aminowise-L IV administered?
Aminowise-L IV is administered by slow intravenous infusion, mixed with a carrier amino-acid solution, calculated by body weight and given under medical supervision.
Is Aminowise-L IV available for PCD pharma franchise?
Yes, Trumac Healthcare offers Aminowise-L IV on monopoly-based PCD pharma franchise and for third-party manufacturing — a high-value hospital SKU.
How should Aminowise-L IV be stored?
Store below 25 °C, protected from light. Do not freeze. Use immediately after opening.
Is Aminowise-L IV WHO-GMP certified?
Yes, Aminowise-L IV is manufactured in WHO-GMP and DCGI-compliant injectable facilities.
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