Dolutegravir 50 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg Tablet
Dolutegravir 50 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg Tablet
Dolutegravir 50 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg — PCD Pharma Franchise, Wholesale Supply & Third Party Manufacturing
Form: Tablet
Class: Fixed-Dose Combination — Integrase inhibitor antiretroviral + NRTI antiretroviral
✓ Pan-India Monopoly PCD
✓ Available Now
Pricing, brochure & monopoly territory within 24 hrs.
Dolutegravir 50 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg Tablet is manufactured and supplied by Trumac Healthcare, a WHO-GMP certified pharmaceutical company in India. This tablet is available for monopoly PCD pharma franchise, wholesale and distributor supply, and third party / contract manufacturing across all Indian states.
Therapeutic Indications
- HIV-1 infection as part of combination antiretroviral therapy
- Preferred first-line regimen component with tenofovir and lamivudine
- Chronic hepatitis B infection
Mechanism of Action
Dolutegravir — Dolutegravir binds to the active site of HIV integrase and blocks the strand-transfer step that inserts viral DNA into the host genome, halting the viral replication cycle.
Lamivudine — Lamivudine is phosphorylated in cells to lamivudine triphosphate, which inhibits HIV reverse transcriptase and hepatitis B polymerase and terminates viral DNA chain elongation.
Tenofovir Disoproxil Fumarate — A prodrug of tenofovir that is phosphorylated to an active form which inhibits HIV reverse transcriptase and hepatitis B polymerase, terminating viral DNA synthesis.
Combining these ingredients in one tablet provides complementary action on the target condition and simplifies therapy compared with taking the components separately.
Dosage & Administration
- Dosage of Dolutegravir 50 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg Tablet must be individualised by the treating physician according to the patient's age, body weight, indication, disease severity and renal or hepatic function.
- Refer to the approved prescribing information for exact dose, frequency, route and duration of therapy.
- Do not exceed the prescribed dose, and complete the full course as advised.
- Dose adjustment may be required in renal or hepatic impairment, in the elderly and in paediatric patients.
- To be dispensed only against a valid prescription from a registered medical practitioner.
Side Effects
- Insomnia and abnormal dreams
- Headache
- Nausea and diarrhoea
- Fatigue
- Kidney function impairment
Contraindications
- Known hypersensitivity to any component of the formulation
- Hypersensitivity reactions; stop if rash with systemic symptoms
- Do not combine with dofetilide
- Hepatitis B co-infection: flare risk on stopping
- Renal impairment; adjust use
- Renal impairment; monitor creatinine and phosphate
Storage
Store below 30 °C in a dry place, protected from light and moisture. Keep in the original packaging until use. Keep out of reach of children. Dispense strictly on a registered medical practitioner's prescription.
PCD Pharma Franchise & Third Party Manufacturing — Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet
- ✓ WHO-GMP certified manufacturing — every batch QC released
- ✓ Monopoly PCD franchise rights at district or state level
- ✓ Third party / contract manufacturing under your own brand
- ✓ Wholesale and distributor supply against drug licence + GST
- ✓ Attractive net rates with healthy PTR / PTS margins
- ✓ Dispatch within 48 hours of payment realisation
Composition: Dolutegravir 50 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg. It is a fixed-dose combination of integrase inhibitor antiretroviral and NRTI antiretroviral. Trumac Healthcare supplies it with complete quality documentation — batch Certificate of Analysis, GMP certificate and statutory invoicing — to PCD franchise partners, stockists, wholesalers and hospital supply chains nationwide.
Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet brings together Dolutegravir (integrase inhibitor antiretroviral), Lamivudine (NRTI antiretroviral) and Tenofovir Disoproxil Fumarate (NRTI antiretroviral) in a single fixed-dose formulation.
PCD franchise partners receive monopoly territory rights at district or state level, promotional support including visual aids and sample literature, competitive net rates with healthy PTR/PTS margins, and dispatch within 48 hours of payment realisation. Third party manufacturing of Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet under your own brand name is available subject to minimum order quantity and valid drug licence and GST documentation.
Frequently Asked Questions
Who manufactures Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet in India?
Trumac Healthcare is a WHO-GMP certified manufacturer and supplier of Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet in India. We supply pan-India to PCD franchise partners, wholesalers, distributors and hospital chains, with full QC documentation and batch Certificate of Analysis. Contact +91 90416 77932 for net rates and availability.
What is Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet used for?
Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet is used for HIV-1 infection as part of combination antiretroviral therapy; preferred first-line regimen component with tenofovir and lamivudine; chronic hepatitis B infection. It should be used as advised by a registered medical practitioner.
Is Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet available for PCD pharma franchise on monopoly basis?
Yes. Dolutegravir 50 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg Tablet is available for monopoly PCD (Propaganda Cum Distribution) pharma franchise across India, with monopoly rights granted at district or state level. Franchise partners receive promotional support, territory protection, competitive net rates with healthy PTR/PTS margins and dedicated backend support.
Do you offer Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate for third party or contract manufacturing?
Yes. Trumac Healthcare undertakes third party manufacturing and contract manufacturing of Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet under your own brand name, subject to minimum order quantity and valid drug licence and GST documentation. Custom pack sizes, carton design and artwork are supported.
Can Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet be supplied on wholesale or distributor basis?
Yes. Beyond PCD franchise, this product is supplied to wholesalers, stockists and distributors at wholesale rates against a valid drug licence and GST registration. Bulk and institutional supply is available on request.
What is the therapeutic class of Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate?
Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate is a fixed-dose combination of integrase inhibitor antiretroviral and NRTI antiretroviral (therapeutic class: Fixed-Dose Combination — Integrase inhibitor antiretroviral + NRTI antiretroviral).
What documentation is provided with each supply?
Every batch ships with a Certificate of Analysis (COA), GMP certificate, drug licence copies and statutory invoice. We also support PCD partner documentation including monopoly agreement, rate contract and product list.
How quickly can an order be dispatched?
Routine PCD orders are dispatched within 48 hours of payment realisation, subject to stock availability and your distance from our depot. For monopoly partners we maintain buffer stock against forecasted monthly off-take.
Is a prescription required for Dolutegravir + Lamivudine + Tenofovir Disoproxil Fumarate Tablet?
Yes. This is a prescription medicine and must be used strictly under the supervision of a registered medical practitioner. PCD franchise distribution is through licensed retail pharmacies and hospital supply chains only.
Ready to start your PCD franchise for Dolutegravir 50 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg Tablet?