Rifampicin 200 mg + Isoniazid 300 mg + Piperine 10 mg Capsule
Rifampicin 200 mg + Isoniazid 300 mg + Piperine 10 mg Capsule
Rifampicin 200 mg + Isoniazid 300 mg + Piperine 10 mg — PCD Pharma Franchise, Wholesale Supply & Third Party Manufacturing
Form: Capsule
Class: Fixed-Dose Combination — First-line anti-tubercular + Bioavailability enhancer
✓ Pan-India Monopoly PCD
✓ Available Now
Pricing, brochure & monopoly territory within 24 hrs.
Rifampicin 200 mg + Isoniazid 300 mg + Piperine 10 mg Capsule is manufactured and supplied by Trumac Healthcare, a WHO-GMP certified pharmaceutical company in India. This capsule is available for monopoly PCD pharma franchise, wholesale and distributor supply, and third party / contract manufacturing across all Indian states.
Therapeutic Indications
- Pulmonary and extra-pulmonary tuberculosis in combination regimens
- Leprosy, as part of multidrug therapy
- Preventive therapy for latent TB infection
- Bioenhancer for rifampicin in fixed-dose anti-tuberculosis combinations
- Improving absorption of curcumin, boswellia and other herbal actives
Mechanism of Action
Rifampicin — Inhibits bacterial DNA-dependent RNA polymerase, blocking RNA synthesis and killing mycobacteria, including slow-growing organisms.
Isoniazid — A prodrug activated by mycobacterial catalase-peroxidase that inhibits synthesis of mycolic acids, essential components of the mycobacterial cell wall.
Piperine — Piperine, the main alkaloid of black pepper, inhibits drug-metabolising enzymes (including CYP3A4 and UGT) and the P-glycoprotein efflux pump in the gut and liver. This increases absorption and blood levels of co-administered compounds such as rifampicin and curcumin.
Combining these ingredients in one capsule provides complementary action on the target condition and simplifies therapy compared with taking the components separately.
Dosage & Administration
- Dosage of Rifampicin 200 mg + Isoniazid 300 mg + Piperine 10 mg Capsule must be individualised by the treating physician according to the patient's age, body weight, indication, disease severity and renal or hepatic function.
- Refer to the approved prescribing information for exact dose, frequency, route and duration of therapy.
- Do not exceed the prescribed dose, and complete the full course as advised.
- Dose adjustment may be required in renal or hepatic impairment, in the elderly and in paediatric patients.
- To be dispensed only against a valid prescription from a registered medical practitioner.
Side Effects
- Orange-red discolouration of urine, sweat and tears
- Hepatitis and raised liver enzymes
- Nausea and abdominal discomfort
- Peripheral neuropathy
- Nausea and vomiting
- Mild stomach irritation or heartburn
- May increase blood levels and effects of other drugs
Contraindications
- Known hypersensitivity to any component of the formulation
- Jaundice or significant liver disease; monitor liver function
- Potent enzyme inducer: reduces efficacy of oral contraceptives, ARVs, anticoagulants
- Acute liver disease or prior isoniazid hepatitis
- Monitor liver function; avoid alcohol
- Hypersensitivity to black pepper or piperine
Storage
Store below 30 °C in a dry place, protected from light and moisture. Keep in the original packaging until use. Keep out of reach of children. Dispense strictly on a registered medical practitioner's prescription.
PCD Pharma Franchise & Third Party Manufacturing — Rifampicin + Isoniazid + Piperine Capsule
- ✓ WHO-GMP certified manufacturing — every batch QC released
- ✓ Monopoly PCD franchise rights at district or state level
- ✓ Third party / contract manufacturing under your own brand
- ✓ Wholesale and distributor supply against drug licence + GST
- ✓ Attractive net rates with healthy PTR / PTS margins
- ✓ Dispatch within 48 hours of payment realisation
Composition: Rifampicin 200 mg + Isoniazid 300 mg + Piperine 10 mg. It is a fixed-dose combination of first-line anti-tubercular and bioavailability enhancer. Trumac Healthcare supplies it with complete quality documentation — batch Certificate of Analysis, GMP certificate and statutory invoicing — to PCD franchise partners, stockists, wholesalers and hospital supply chains nationwide.
Rifampicin + Isoniazid + Piperine Capsule brings together Rifampicin (first-line anti-tubercular), Isoniazid (first-line anti-tubercular) and Piperine (bioavailability enhancer) in a single fixed-dose formulation.
PCD franchise partners receive monopoly territory rights at district or state level, promotional support including visual aids and sample literature, competitive net rates with healthy PTR/PTS margins, and dispatch within 48 hours of payment realisation. Third party manufacturing of Rifampicin + Isoniazid + Piperine Capsule under your own brand name is available subject to minimum order quantity and valid drug licence and GST documentation.
Frequently Asked Questions
Who manufactures Rifampicin + Isoniazid + Piperine Capsule in India?
Trumac Healthcare is a WHO-GMP certified manufacturer and supplier of Rifampicin + Isoniazid + Piperine Capsule in India. We supply pan-India to PCD franchise partners, wholesalers, distributors and hospital chains, with full QC documentation and batch Certificate of Analysis. Contact +91 90416 77932 for net rates and availability.
What is Rifampicin + Isoniazid + Piperine Capsule used for?
Rifampicin + Isoniazid + Piperine Capsule is used for pulmonary and extra-pulmonary tuberculosis in combination regimens; leprosy, as part of multidrug therapy; preventive therapy for latent TB infection; bioenhancer for rifampicin in fixed-dose anti-tuberculosis combinations. It should be used as advised by a registered medical practitioner.
Is Rifampicin + Isoniazid + Piperine Capsule available for PCD pharma franchise on monopoly basis?
Yes. Rifampicin 200 mg + Isoniazid 300 mg + Piperine 10 mg Capsule is available for monopoly PCD (Propaganda Cum Distribution) pharma franchise across India, with monopoly rights granted at district or state level. Franchise partners receive promotional support, territory protection, competitive net rates with healthy PTR/PTS margins and dedicated backend support.
Do you offer Rifampicin + Isoniazid + Piperine for third party or contract manufacturing?
Yes. Trumac Healthcare undertakes third party manufacturing and contract manufacturing of Rifampicin + Isoniazid + Piperine Capsule under your own brand name, subject to minimum order quantity and valid drug licence and GST documentation. Custom pack sizes, carton design and artwork are supported.
Can Rifampicin + Isoniazid + Piperine Capsule be supplied on wholesale or distributor basis?
Yes. Beyond PCD franchise, this product is supplied to wholesalers, stockists and distributors at wholesale rates against a valid drug licence and GST registration. Bulk and institutional supply is available on request.
What is the therapeutic class of Rifampicin + Isoniazid + Piperine?
Rifampicin + Isoniazid + Piperine is a fixed-dose combination of first-line anti-tubercular and bioavailability enhancer (therapeutic class: Fixed-Dose Combination — First-line anti-tubercular + Bioavailability enhancer).
What documentation is provided with each supply?
Every batch ships with a Certificate of Analysis (COA), GMP certificate, drug licence copies and statutory invoice. We also support PCD partner documentation including monopoly agreement, rate contract and product list.
How quickly can an order be dispatched?
Routine PCD orders are dispatched within 48 hours of payment realisation, subject to stock availability and your distance from our depot. For monopoly partners we maintain buffer stock against forecasted monthly off-take.
Is a prescription required for Rifampicin + Isoniazid + Piperine Capsule?
Yes. This is a prescription medicine and must be used strictly under the supervision of a registered medical practitioner. PCD franchise distribution is through licensed retail pharmacies and hospital supply chains only.
Ready to start your PCD franchise for Rifampicin 200 mg + Isoniazid 300 mg + Piperine 10 mg Capsule?