Simvastatin 20 mg + Ramipril 5 mg + Atenolol 50 mg + Hydrochlorothiazide 12.5 mg + Aspirin 100 mg Capsule
Simvastatin 20 mg + Ramipril 5 mg + Atenolol 50 mg + Hydrochlorothiazide 12.5 mg + Aspirin 100 mg Capsule
Simvastatin 20 mg + Ramipril 5 mg + Atenolol 50 mg + Hydrochlorothiazide 12.5 mg + Aspirin 100 mg — PCD Pharma Franchise, Wholesale Supply & Third Party Manufacturing
Form: Capsule
Class: Fixed-Dose Combination — Cholesterol-lowering statin + ACE inhibitor + Cardioselective beta blocker
✓ Pan-India Monopoly PCD
✓ Available Now
Pricing, brochure & monopoly territory within 24 hrs.
Simvastatin 20 mg + Ramipril 5 mg + Atenolol 50 mg + Hydrochlorothiazide 12.5 mg + Aspirin 100 mg Capsule is manufactured and supplied by Trumac Healthcare, a WHO-GMP certified pharmaceutical company in India. This capsule is available for monopoly PCD pharma franchise, wholesale and distributor supply, and third party / contract manufacturing across all Indian states.
Therapeutic Indications
- Lowering LDL cholesterol in hypercholesterolaemia and mixed dyslipidaemia
- Reducing risk of heart attack and stroke in high-risk patients
- Reduction of cardiovascular risk in high-risk patients
- Hypertension, alone or with other antihypertensives
- Stable angina pectoris
Mechanism of Action
Simvastatin — Simvastatin is a prodrug activated in the liver, where it inhibits HMG-CoA reductase, the key enzyme in cholesterol synthesis. Lower liver cholesterol increases LDL receptors, which clear more LDL cholesterol from the blood.
Ramipril — Ramipril is converted to ramiprilat, which inhibits angiotensin-converting enzyme. Lower angiotensin II relaxes blood vessels and reduces aldosterone, lowering blood pressure and helping protect the heart and kidneys.
Atenolol — Atenolol selectively blocks beta-1 receptors in the heart, slowing heart rate, reducing force of contraction and lowering renin release, which reduces blood pressure and cardiac oxygen demand.
Hydrochlorothiazide — Inhibits sodium-chloride reabsorption in the distal convoluted tubule, increasing excretion of salt and water and lowering blood pressure.
Aspirin — Irreversibly inhibits platelet cyclo-oxygenase, blocking thromboxane A2 formation for the platelet's lifespan and thereby reducing platelet aggregation and clot formation.
Combining these ingredients in one capsule provides complementary action on the target condition and simplifies therapy compared with taking the components separately.
Dosage & Administration
- Dosage of Simvastatin 20 mg + Ramipril 5 mg + Atenolol 50 mg + Hydrochlorothiazide 12.5 mg + Aspirin 100 mg Capsule must be individualised by the treating physician according to the patient's age, body weight, indication, disease severity and renal or hepatic function.
- Refer to the approved prescribing information for exact dose, frequency, route and duration of therapy.
- Do not exceed the prescribed dose, and complete the full course as advised.
- Dose adjustment may be required in renal or hepatic impairment, in the elderly and in paediatric patients.
- To be dispensed only against a valid prescription from a registered medical practitioner.
Side Effects
- Muscle aches or weakness
- Raised liver enzymes
- Constipation, abdominal pain or flatulence
- Dry cough
- Dizziness and low blood pressure
- Raised potassium levels
- Slow heart rate
Contraindications
- Known hypersensitivity to any component of the formulation
- Active liver disease or persistently raised liver enzymes
- Contraindicated in pregnancy and breastfeeding
- Pregnancy (foetal toxicity)
- History of angioedema
- Bradycardia, heart block or cardiogenic shock
Storage
Store below 30 °C in a dry place, protected from light and moisture. Keep in the original packaging until use. Keep out of reach of children. Dispense strictly on a registered medical practitioner's prescription.
PCD Pharma Franchise & Third Party Manufacturing — Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule
- ✓ WHO-GMP certified manufacturing — every batch QC released
- ✓ Monopoly PCD franchise rights at district or state level
- ✓ Third party / contract manufacturing under your own brand
- ✓ Wholesale and distributor supply against drug licence + GST
- ✓ Attractive net rates with healthy PTR / PTS margins
- ✓ Dispatch within 48 hours of payment realisation
Composition: Simvastatin 20 mg + Ramipril 5 mg + Atenolol 50 mg + Hydrochlorothiazide 12.5 mg + Aspirin 100 mg. It is a fixed-dose combination of cholesterol-lowering statin, ACE inhibitor, cardioselective beta blocker and other ingredients. Trumac Healthcare supplies it with complete quality documentation — batch Certificate of Analysis, GMP certificate and statutory invoicing — to PCD franchise partners, stockists, wholesalers and hospital supply chains nationwide.
Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule brings together Simvastatin (cholesterol-lowering statin), Ramipril (ACE inhibitor), Atenolol (cardioselective beta blocker), Hydrochlorothiazide (thiazide diuretic) and Aspirin (antiplatelet agent) in a single fixed-dose formulation.
PCD franchise partners receive monopoly territory rights at district or state level, promotional support including visual aids and sample literature, competitive net rates with healthy PTR/PTS margins, and dispatch within 48 hours of payment realisation. Third party manufacturing of Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule under your own brand name is available subject to minimum order quantity and valid drug licence and GST documentation.
Frequently Asked Questions
Who manufactures Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule in India?
Trumac Healthcare is a WHO-GMP certified manufacturer and supplier of Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule in India. We supply pan-India to PCD franchise partners, wholesalers, distributors and hospital chains, with full QC documentation and batch Certificate of Analysis. Contact +91 90416 77932 for net rates and availability.
What is Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule used for?
Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule is used for lowering LDL cholesterol in hypercholesterolaemia and mixed dyslipidaemia; reducing risk of heart attack and stroke in high-risk patients; reduction of cardiovascular risk in high-risk patients; hypertension, alone or with other antihypertensives. It should be used as advised by a registered medical practitioner.
Is Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule available for PCD pharma franchise on monopoly basis?
Yes. Simvastatin 20 mg + Ramipril 5 mg + Atenolol 50 mg + Hydrochlorothiazide 12.5 mg + Aspirin 100 mg Capsule is available for monopoly PCD (Propaganda Cum Distribution) pharma franchise across India, with monopoly rights granted at district or state level. Franchise partners receive promotional support, territory protection, competitive net rates with healthy PTR/PTS margins and dedicated backend support.
Do you offer Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin for third party or contract manufacturing?
Yes. Trumac Healthcare undertakes third party manufacturing and contract manufacturing of Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule under your own brand name, subject to minimum order quantity and valid drug licence and GST documentation. Custom pack sizes, carton design and artwork are supported.
Can Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule be supplied on wholesale or distributor basis?
Yes. Beyond PCD franchise, this product is supplied to wholesalers, stockists and distributors at wholesale rates against a valid drug licence and GST registration. Bulk and institutional supply is available on request.
What is the therapeutic class of Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin?
Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin is a fixed-dose combination of cholesterol-lowering statin, ACE inhibitor, cardioselective beta blocker and other ingredients (therapeutic class: Fixed-Dose Combination — Cholesterol-lowering statin + ACE inhibitor + Cardioselective beta blocker).
What documentation is provided with each supply?
Every batch ships with a Certificate of Analysis (COA), GMP certificate, drug licence copies and statutory invoice. We also support PCD partner documentation including monopoly agreement, rate contract and product list.
How quickly can an order be dispatched?
Routine PCD orders are dispatched within 48 hours of payment realisation, subject to stock availability and your distance from our depot. For monopoly partners we maintain buffer stock against forecasted monthly off-take.
Is a prescription required for Simvastatin + Ramipril + Atenolol + Hydrochlorothiazide + Aspirin Capsule?
Yes. This is a prescription medicine and must be used strictly under the supervision of a registered medical practitioner. PCD franchise distribution is through licensed retail pharmacies and hospital supply chains only.
Ready to start your PCD franchise for Simvastatin 20 mg + Ramipril 5 mg + Atenolol 50 mg + Hydrochlorothiazide 12.5 mg + Aspirin 100 mg Capsule?