Acomust-300 SR Tablet
Acotiamide 300 mg Sustained Release Tablets — Once-Daily Prokinetic (DCGI Approved)
| Composition | Acotiamide 300 mg (Sustained Release) — DCGI Approved Molecule |
|---|---|
| Dosage Form | Sustained Release Tablet |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 1 x 10 Tablets |
| MRP | ₹ 4900 |
| Therapy | G.P. + Gastroenterology — Prokinetic / Acetylcholinesterase Inhibitor (SR) |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Acomust-300 SR Tablet
Acomust-300 SR Tablet is a sustained-release formulation of Acotiamide 300 mg from Trumac Healthcare — a DCGI-approved once-daily prokinetic for the management of functional dyspepsia. The SR matrix releases acotiamide gradually over the dosing interval, maintaining therapeutic plasma concentrations with a single daily dose, improving adherence over the conventional thrice-daily regimen.
Acotiamide acts peripherally on the enteric nervous system by inhibiting acetylcholinesterase and antagonising pre-synaptic muscarinic M1/M2 autoreceptors, enhancing acetylcholine release at the myenteric plexus. The result is improved gastric accommodation, faster gastric emptying and relief from early satiety, postprandial fullness and epigastric burning — the hallmark symptoms of postprandial distress syndrome.
Acomust-300 SR is manufactured in WHO-GMP certified facilities and is positioned as a premium, high-margin SKU for any gastroenterology franchise. The DCGI-approved status supports prescription credibility with gastroenterologists and general physicians.
Indications
- Functional dyspepsia — postprandial-distress and epigastric-pain subtypes
- Early satiety; postprandial fullness; chronic upper-abdominal bloating
- Non-erosive reflux disease with motility component
- Adjunct in mild diabetic gastroparesis
Mechanism of Action
Acotiamide produces dual peripheral cholinergic enhancement: it inhibits acetylcholinesterase in the upper GI tract and blocks pre-synaptic muscarinic M1 and M2 autoreceptors. Together these actions raise acetylcholine availability at the myenteric plexus, improving gastric accommodation and antral motility without central dopaminergic effects.
Dosage & Administration
Adults: one Acomust-300 SR tablet once daily, before a meal, for 4 weeks. Re-evaluate after 4 weeks. To be prescribed by a physician. Swallow whole; do not crush or chew.
Side Effects
Diarrhoea, constipation, nausea, headache, mild abdominal discomfort. Rare: hepatic enzyme elevation, hypersensitivity reactions.
Contraindications & Precautions
Hypersensitivity to acotiamide. Use with caution in hepatic impairment. Not recommended in children, pregnancy or lactation unless specifically advised by a physician. Do not crush or break the SR tablet.
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Acomust-300 SR Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Acomust-300 SR Tablet used for?
Acomust-300 SR Tablet contains Acotiamide 300 mg in a sustained-release form and is used for functional dyspepsia — particularly postprandial-distress syndrome with early satiety, fullness and bloating.
Is Acomust-300 a DCGI-approved molecule?
Yes, Acotiamide is a DCGI-approved molecule. Acomust-300 SR is Trumac's once-daily sustained-release formulation, manufactured under WHO-GMP conditions.
Why a once-daily SR formulation?
The sustained-release matrix maintains therapeutic plasma levels of acotiamide over 24 hours, replacing the conventional thrice-daily regimen and significantly improving patient adherence.
Is Acomust-300 SR available for PCD pharma franchise?
Yes, Trumac Healthcare offers Acomust-300 SR on monopoly-based PCD pharma franchise as a premium gastroenterology SKU, and for third-party manufacturing.
How should Acomust-300 SR be stored?
Store below 30 °C in a dry place, away from direct sunlight and moisture. Swallow the tablet whole; do not crush or chew.
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