Cefob-125 Dry Syrup
Cefuroxime 125 mg / 5 ml Dry Syrup — Paediatric Second-Gen Cephalosporin
| Composition | Cefuroxime 125 mg / 5 ml (Dry Syrup with Water) |
|---|---|
| Dosage Form | Dry Syrup |
| Pack Type | Bottle with Water |
| Pack Size | 30 ml / 60 ml Bottle |
| MRP | ₹ 137.5 |
| Therapy | Antibiotic + G.P. + Orthopaedics — Second-Generation Cephalosporin |
| Storage | Dry powder below 30 °C. After reconstitution, refrigerate and use within 10 days. |
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About Cefob-125 Dry Syrup
Cefob-125 Dry Syrup contains Cefuroxime Axetil 125 mg per 5 ml when reconstituted — the paediatric oral cephalosporin for bacterial otitis media, sinusitis, pharyngitis, lower respiratory tract infections and uncomplicated UTI in children.
Cefuroxime Axetil is the oral prodrug form of cefuroxime, hydrolysed in intestinal mucosa to release active cefuroxime. The dry-syrup format allows accurate paediatric dosing while maintaining stability of the active drug until point-of-dispensing reconstitution.
Cefob-125 Dry Syrup is manufactured by Trumac Healthcare under WHO-GMP conditions. Available for monopoly-based PCD pharma franchise and third-party manufacturing — a high-volume paediatric SKU.
Indications
- Paediatric acute otitis media
- Streptococcal pharyngitis (10-day course)
- Acute sinusitis
- Community-acquired pneumonia
- Uncomplicated UTI in children
- Skin and soft-tissue infections
Mechanism of Action
Cefuroxime is a second-generation cephalosporin that binds penicillin-binding proteins, inhibiting peptidoglycan cross-linking and producing bacterial cell wall destabilisation. Compared with first-generation cephalosporins, cefuroxime has enhanced gram-negative activity (H. influenzae, M. catarrhalis, E. coli) plus retained gram-positive coverage.
Dosage & Administration
Children: 15–30 mg/kg/day in two divided doses for 7–10 days. Reconstitute with supplied water; shake well; refrigerate after reconstitution.
Side Effects
Diarrhoea, nausea, vomiting, mild skin rash. Rare: pseudomembranous colitis, anaphylaxis, severe skin reactions, transient hepatic enzyme elevation. Cross-reactivity with penicillin allergy (~5–10%).
Contraindications & Precautions
Hypersensitivity to cephalosporins. Severe penicillin allergy. Caution in renal impairment (dose adjustment). Caution in GI disease.
Storage
Dry powder below 30 °C. After reconstitution, refrigerate and use within 10 days.
Cefob-125 Dry Syrup is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Cefob-125 Dry Syrup used for?
Cefob-125 contains Cefuroxime 125 mg/5 ml for paediatric otitis media, streptococcal pharyngitis, sinusitis, pneumonia, UTI and skin infections.
How should the dry syrup be reconstituted?
Add the supplied water up to the marked line, shake well until uniform. Refrigerate after reconstitution and use within 10 days. Shake before each dose.
Is Cefob-125 available for PCD pharma franchise?
Yes, on monopoly-based PCD pharma franchise and third-party manufacturing.
How should Cefob-125 be stored?
Dry powder below 30 °C. After reconstitution, refrigerate (2–8 °C) and use within 10 days.
Is Cefob-125 WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
Related Products
- Cefob-250 Tablet — Cefuroxime Axetil 250 mg
- Cefob-500 Tablet — Cefuroxime Axetil 500 mg
- Cefob-CV Dry Syrup — Cefuroxime 125 mg + Clavulanic Acid 31.25 mg per 5 ml (Dry Syrup)