Calimac-Joints Capsule
Calcium Carbonate 600 mg + Undenatured Collagen Peptide Type II Capsules — Joint Cartilage Support
| Composition | Calcium Carbonate 600 mg + Undenatured Collagen Peptide Type II |
|---|---|
| Dosage Form | Soft Gelatin Capsule |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10 Capsules |
| MRP | ₹ 2550 |
| Therapy | Orthopaedics + Gynaecology + G.P. — Calcium + Joint Cartilage Support |
| Storage | Store below 25 °C in a dry place, protected from heat and direct sunlight. |
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About Calimac-Joints Capsule
Calimac-Joints Capsule combines Calcium Carbonate 600 mg with Undenatured Collagen Peptide Type II (UC-II) — addressing both bone density and joint cartilage health in a single dose. UC-II is a patented form of native (undenatured) chicken sternum collagen that has shown efficacy in osteoarthritis through an oral tolerisation mechanism.
Unlike hydrolysed collagen which is broken into peptides, UC-II retains its native triple-helical structure, allowing it to interact with gut-associated lymphoid tissue (Peyer’s patches) to modulate immune response against joint collagen. Clinical trials have shown UC-II significantly improves joint pain, stiffness and function in osteoarthritis at doses as low as 40 mg/day.
Calimac-Joints is manufactured by Trumac Healthcare under WHO-GMP conditions. Available for monopoly-based PCD pharma franchise and third-party manufacturing — a specialty joint health SKU.
Indications
- Osteoarthritis of knee, hip and other joints
- Joint pain and stiffness
- Cartilage support in athletes and overuse injuries
- Adjunct to NSAIDs in osteoarthritis
- Bone-and-joint comprehensive support
Mechanism of Action
UC-II works through oral tolerisation — small intact collagen molecules interact with Peyer's patches in the gut, modulating immune response against joint collagen and reducing autoimmune-mediated cartilage destruction. This down-regulates inflammatory cytokines (TNF-α, IL-1β) in joint tissue. Calcium Carbonate supports bone density.
Dosage & Administration
Adults: 1 capsule once daily on an empty stomach (for UC-II) — typically taken at bedtime, or as directed by physician.
Side Effects
Generally well tolerated. Mild GI upset. Rare: hypersensitivity to chicken-derived collagen. Hypercalcaemia with excessive dosing.
Contraindications & Precautions
Hypersensitivity to chicken or egg products. Hypercalcaemia. Hyperparathyroidism. Pregnancy and lactation (limited safety data with UC-II).
Storage
Store below 25 °C in a dry place, protected from heat and direct sunlight.
Calimac-Joints Capsule is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Calimac-Joints Capsule used for?
Calimac-Joints combines Calcium with Undenatured Collagen Type II (UC-II) for osteoarthritis, joint pain, cartilage support and combined bone-joint health.
What is Undenatured Collagen Type II (UC-II)?
UC-II is patented native chicken sternum collagen that retains its triple-helical structure. It works by oral tolerisation — modulating immune response against joint collagen — and has clinical evidence in osteoarthritis at doses as low as 40 mg/day.
Is Calimac-Joints available for PCD pharma franchise?
Yes, on monopoly-based PCD pharma franchise and third-party manufacturing — a specialty joint health SKU.
How should Calimac-Joints be stored?
Store below 25 °C in a dry place, protected from heat and direct sunlight.
Is Calimac-Joints WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
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