Divalmac-250 Tablet
Divalproex Sodium 250 mg Extended Release Tablets
| Composition | Divalproex 250 mg Extended Release |
|---|---|
| Dosage Form | Extended Release Tablet |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10 Tablets |
| MRP | ₹ 979 |
| Therapy | Neurology — Antiepileptic + Mood Stabiliser |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Divalmac-250 Tablet
Divalmac-250 ER Tablet contains Divalproex Sodium 250 mg in an extended-release format — a stable coordination compound containing valproic acid and sodium valproate in 1:1 molar ratio. Used for epilepsy, bipolar disorder maintenance and migraine prophylaxis.
Divalproex provides broad-spectrum antiepileptic activity covering generalised tonic-clonic, absence, myoclonic and focal seizures. The ER formulation supports once-daily dosing with smoother plasma levels.
Manufactured by Trumac Healthcare under WHO-GMP. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Generalised and focal-onset seizures
- Bipolar disorder (manic episodes & maintenance)
- Migraine prophylaxis
- Status epilepticus (alternative formulations)
Mechanism of Action
Divalproex enhances GABA-ergic neurotransmission and modulates voltage-gated sodium channels. Inhibits histone deacetylase. Broad mechanism produces wide-spectrum antiepileptic activity.
Dosage & Administration
Adults: 500–1000 mg/day in 1–2 divided doses; titrate based on serum levels (50–100 mcg/ml). Adjust in hepatic impairment.
Side Effects
GI upset, weight gain, tremor, hair loss, elevated liver enzymes. Serious: hepatotoxicity, pancreatitis, thrombocytopenia, teratogenic.
Contraindications & Precautions
Pregnancy (highly teratogenic — neural tube defects). Hepatic disease. Urea cycle disorders. Mitochondrial disorders.
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Divalmac-250 Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Divalmac-250 Tablet used for?
Divalmac-250 Tablet contains Divalproex 250 mg Extended Release. Used as per the indications described above.
How should Divalmac-250 Tablet be taken?
As directed by your physician. Complete the prescribed course.
Is Divalmac-250 Tablet available for PCD pharma franchise?
Yes, Trumac Healthcare offers Divalmac-250 Tablet on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Divalmac-250 Tablet be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Divalmac-250 Tablet WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
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