Makclav-625 Tablet
Amoxicillin 500 mg + Clavulanic Acid 125 mg Tablets — Standard 625 Strength
| Composition | Amoxycillin Trihydrate 500 mg + Potassium Clavulanate 125 mg |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10, 10 x 1 x 10, or 10 x 6 Packs |
| MRP | ₹ 1229.7 |
| Therapy | G.P. / Family Medicine / ID — Oral Beta-Lactam + BLI |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Makclav-625 Tablet
Makclav-625 Tablet is the most-prescribed adult oral antibiotic strength — Amoxicillin 500 mg + Clavulanic Acid 125 mg. Standard for community-acquired pneumonia, sinusitis, otitis, UTI, and skin/soft-tissue infections. Available in multiple pack sizes (10×10, 10×1×10, 10×6) and Akums-sourced variants for institutional supply.
Manufactured by Trumac Healthcare under WHO-GMP. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Community-acquired pneumonia
- Sinusitis
- Acute otitis media
- Complicated UTI
- Cellulitis
- Dental infections
- Animal/human bite wounds (prophylactic)
Mechanism of Action
Amoxicillin is a beta-lactam (aminopenicillin) that binds penicillin-binding proteins (PBPs) inhibiting bacterial cell wall peptidoglycan cross-linking. Clavulanic Acid is a beta-lactamase inhibitor — irreversibly inactivates bacterial beta-lactamases protecting Amoxicillin from enzymatic hydrolysis. The combination extends Amoxicillin's spectrum to include beta-lactamase-producing strains of E. coli, H. influenzae, M. catarrhalis, and many anaerobes.
Dosage & Administration
Adults: 1 tablet every 8–12 hours for 5–10 days based on infection severity.
Side Effects
Diarrhoea (more common than amoxicillin alone — Clavulanate-related), GI upset, rash, candidiasis. Cholestatic hepatitis (rare). C. difficile colitis.
Contraindications & Precautions
Penicillin/cephalosporin hypersensitivity, history of Amoxicillin-Clavulanate-induced jaundice or hepatic dysfunction, infectious mononucleosis (rash), severe renal impairment (dose adjust).
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Makclav-625 Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Makclav-625 Tablet used for?
Makclav-625 Tablet contains Amoxycillin Trihydrate 500 mg + Potassium Clavulanate 125 mg. Used as per the indications described above.
How should Makclav-625 Tablet be taken?
As directed by your physician. Complete the prescribed course.
Is Makclav-625 Tablet available for PCD pharma franchise?
Yes, Trumac Healthcare offers Makclav-625 Tablet on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Makclav-625 Tablet be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Makclav-625 Tablet WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
Related Products
- Makclav-625 LB Tablet — Amoxycillin 500 mg + Potassium Clavulanate 125 mg + Lactobacillus Spores
- Makclav-375 Tablet — Amoxycillin Trihydrate 250 mg + Potassium Clavulanate 125 mg
- Makclav Dry Syrup 60 ml — Amoxycillin Trihydrate 200 mg + Clavulanic Acid 28.5 mg per 5 ml