Glicam-0.5 Tablet
Glimepiride 0.5 mg — Sulphonylurea Tablet
| Composition | Glimepiride 0.5 mg |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Box |
| Pack Size | 10 x 10 (Blister) |
| MRP | ₹ 350 |
| Therapy | Cardiac + Diabetic — Third-generation sulphonylurea |
| Storage | Store below 25°C. |
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About Glicam-0.5 Tablet
Glicam-0.5 Tablet contains Glimepiride 0.5 mg, a third-generation sulphonylurea designed for once-daily dosing in type-2 diabetes mellitus. The drug has lower hypoglycaemia risk than older sulphonylureas and minimal weight-gain effect.
It is indicated as monotherapy or in combination with metformin for adult patients with type-2 diabetes inadequately controlled by lifestyle measures alone.
Camrut Healthcare manufactures the Glicam range under WHO-GMP conditions for PCD pharma franchise across India.
Indications
- Type-2 diabetes mellitus inadequately controlled by diet/exercise
- Adjunct to metformin
- Patients preferring once-daily oral therapy
Mechanism of Action
Glimepiride closes ATP-sensitive K+ channels on pancreatic beta-cell membranes (via the SUR1 receptor subunit), depolarising the cell and triggering calcium-mediated insulin exocytosis. It has lower binding to extra-pancreatic SUR2 isoforms compared to glibenclamide, giving a better cardiovascular profile.
Dosage & Administration
['Adults: 1 tablet once daily, immediately before breakfast', 'Titrate gradually at 1–2 week intervals based on glycaemia', 'Maximum 8 mg/day', 'Use under physician supervision']
Side Effects
['Hypoglycaemia (lower risk than glibenclamide)', 'Weight gain (modest)', 'GI upset', 'Hypersensitivity reactions (rare)', 'Hyponatraemia (rare)']
Contraindications & Precautions
['Type-1 diabetes', 'Diabetic ketoacidosis', 'Severe renal/hepatic impairment', 'Pregnancy and breastfeeding', 'Sulphonamide hypersensitivity']
Storage
Store below 25°C.
Glicam-0.5 Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
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Related Products
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