Makclav-DS Dry Syrup 60 ml
Amoxicillin 400 mg + Clavulanic Acid 57 mg Dry Syrup — DS 60 ml Family Pack
| Composition | Amoxycillin Trihydrate 400 mg + Clavulanic Acid 57 mg per 5 ml |
|---|---|
| Dosage Form | Dry Syrup (Reconstituted) |
| Pack Type | PET Bottle + Water Sachet |
| Pack Size | 60 ml After Reconstitution |
| MRP | ₹ 297 |
| Therapy | Paediatrics — Higher-Strength Paediatric DS Beta-Lactam |
| Storage | Refrigerate after reconstitution. Use within 7 days. |
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About Makclav-DS Dry Syrup 60 ml
Makclav-DS Dry Syrup 60 ml is the family-pack DS strength — same Amoxicillin 400 mg + Clavulanic 57 mg formulation in 60 ml bottle for longer paediatric courses.
Manufactured by Trumac Healthcare under WHO-GMP. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Older paediatric patients requiring extended courses
- Family with multiple children needing antibiotic
Mechanism of Action
Amoxicillin is a beta-lactam (aminopenicillin) that binds penicillin-binding proteins (PBPs) inhibiting bacterial cell wall peptidoglycan cross-linking. Clavulanic Acid is a beta-lactamase inhibitor — irreversibly inactivates bacterial beta-lactamases protecting Amoxicillin from enzymatic hydrolysis. The combination extends Amoxicillin's spectrum to include beta-lactamase-producing strains of E. coli, H. influenzae, M. catarrhalis, and many anaerobes.
Dosage & Administration
Children: 45 mg/kg/day of Amoxicillin component twice daily.
Side Effects
Diarrhoea (more common than amoxicillin alone — Clavulanate-related), GI upset, rash, candidiasis. Cholestatic hepatitis (rare). C. difficile colitis.
Contraindications & Precautions
Penicillin/cephalosporin hypersensitivity, history of Amoxicillin-Clavulanate-induced jaundice or hepatic dysfunction, infectious mononucleosis (rash), severe renal impairment (dose adjust).
Storage
Refrigerate after reconstitution. Use within 7 days.
Makclav-DS Dry Syrup 60 ml is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Makclav-DS Dry Syrup 60 ml used for?
Makclav-DS Dry Syrup 60 ml contains Amoxycillin Trihydrate 400 mg + Clavulanic Acid 57 mg per 5 ml. Used as per the indications described above.
How should Makclav-DS Dry Syrup 60 ml be taken?
As directed by your physician. Complete the prescribed course.
Is Makclav-DS Dry Syrup 60 ml available for PCD pharma franchise?
Yes, Trumac Healthcare offers Makclav-DS Dry Syrup 60 ml on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Makclav-DS Dry Syrup 60 ml be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Makclav-DS Dry Syrup 60 ml WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
Related Products
- Makclav-DS Dry Syrup 30 ml — Amoxycillin Trihydrate 400 mg + Clavulanic Acid 57 mg per 5 ml
- Makclav Dry Syrup 60 ml — Amoxycillin Trihydrate 200 mg + Clavulanic Acid 28.5 mg per 5 ml
- Makclav-ES Dry Syrup — Amoxycillin Trihydrate 600 mg + Clavulanic Acid 42.9 mg per 5 ml