Metrofix-Plus Tablet
Metronidazole 200 mg + Loperamide 2 mg + Dicyclomine 20 mg Tablets
| Composition | Metronidazole 200 mg + Loperamide 2 mg + Dicyclomine 20 mg |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10 Tablets |
| MRP | ₹ 1300 |
| Therapy | G.P. / Gastro — Antiprotozoal + Anti-Diarrhoeal + Antispasmodic |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Metrofix-Plus Tablet
Metrofix-Plus Tablet combines Metronidazole 200 mg with Loperamide 2 mg and Dicyclomine 20 mg — triple-action for acute infective diarrhoea (especially amoebic dysentery, giardiasis with cramps). Metronidazole kills protozoa, Loperamide reduces stool frequency, Dicyclomine relieves cramps.
Manufactured by Trumac Healthcare under WHO-GMP. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Acute amoebic dysentery
- Giardiasis with cramps
- Traveller's diarrhoea (suspected protozoal)
- Mixed infective diarrhoea with cramps
Mechanism of Action
Metronidazole is a nitroimidazole prodrug — activated by bacterial/protozoal reductases to form cytotoxic nitro radical anions that damage DNA. Active against obligate anaerobes (Bacteroides, Clostridium), microaerophiles (H. pylori), and protozoa (Giardia, Entamoeba, Trichomonas). Loperamide slows intestinal transit. Dicyclomine relieves smooth muscle spasm.
Dosage & Administration
Adults: 1 tablet 2–3 times daily after meals.
Side Effects
Metallic taste, nausea, GI upset, headache, neuropathy with prolonged use, disulfiram-like reaction with alcohol. Constipation, dry mouth, drowsiness.
Contraindications & Precautions
First trimester pregnancy, lactation, severe hepatic impairment, history of blood dyscrasia, alcohol consumption. Active dysentery (limited Loperamide use), narrow-angle glaucoma.
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Metrofix-Plus Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Metrofix-Plus Tablet used for?
Metrofix-Plus Tablet contains Metronidazole 200 mg + Loperamide 2 mg + Dicyclomine 20 mg. Used as per the indications described above.
How should Metrofix-Plus Tablet be taken?
As directed by your physician. Complete the prescribed course.
Is Metrofix-Plus Tablet available for PCD pharma franchise?
Yes, Trumac Healthcare offers Metrofix-Plus Tablet on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Metrofix-Plus Tablet be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Metrofix-Plus Tablet WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
Related Products
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- Lopawise-2 Tablet — Loperamide 2 mg
- Mefrut-Spas Tablet — Mefenamic Acid 250 mg + Dicyclomine HCL 10 mg