Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet
Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet
WHO-GMP Manufacturer & PCD Pharma Franchise Supplier in India
Form: Tablet
Class: Venous nitrate + arterial vasodilator combination (heart failure)
✓ Pan-India Monopoly PCD
✓ 1 Brand Options
Pricing, brochure & monopoly territory within 24 hrs.
For chemists, distributors and doctors: Isoplex-HF (isosorbide dinitrate 20 mg + hydralazine 37.5 mg tablet) is available from Trumac Healthcare on a PCD franchise with monopoly rights for your district, and as wholesale stock for licensed distributors. No franchise fee; first order from ₹25,000 – work out your margin with the PTR / PTS calculator.
Our Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet Brand Options (1 option)
Trumac Healthcare manufactures and supplies the following Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet brands for PCD pharma distribution. Click any brand to view full specifications and packaging.
Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet is manufactured under WHO-GMP-certified conditions by Trumac Healthcare and supplied for PCD/Propaganda-cum-Distribution pharma franchise on monopoly basis across India. Whether you are a PCD distributor, stockist or retail chemist, our Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg formulation comes with full quality assurance, regulatory documentation and reliable pan-India despatch.
Part of our PCD pharma franchise range, available on a monopoly basis – see the ophthalmic PCD franchise product list. No franchise fee; minimum first order ₹25,000 – cost and documents.
Therapeutic Indications
- Heart failure with reduced ejection fraction (HFrEF)
- HF in African-origin patients on background ACE inhibitor / ARB therapy
- ACE inhibitor / ARB-intolerant patients with HF
- Chronic refractory heart failure
Mechanism of Action
Isosorbide Dinitrate is converted to nitric oxide in vascular smooth muscle, predominantly venodilating and reducing preload. Hydralazine is a direct arterial vasodilator (mechanism uncertain — possibly through release of nitric oxide and inhibition of inositol triphosphate-induced calcium release). The combination provides balanced reduction in preload and afterload.
Dosage & Administration
- Adults: 1 tablet three times daily (titrate from lower starting dose)
- Take with food to reduce GI side effects
- Use under cardiologist supervision
- Monitor BP and renal function
Side Effects
- Headache (very common — nitrate-mediated)
- Postural hypotension
- Reflex tachycardia
- SLE-like syndrome (hydralazine, dose-dependent)
- Fluid retention
Contraindications
- Severe aortic stenosis
- Hypertrophic obstructive cardiomyopathy
- Recent MI with hypotension
- Concurrent PDE-5 inhibitors (Sildenafil etc)
- Hydralazine-induced SLE history
Storage
Store below 25°C.
PCD Pharma Franchise for Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet
- ✓ WHO-GMP certified manufacturing facility
- ✓ Pan-India monopoly distribution rights available
- ✓ Multiple pack sizes: 10 x 10 (Alu Alu)
- ✓ Trade-friendly PTR / PTS margins
- ✓ Free promotional material on request
- ✓ Full DCGI documentation and quality certificates supplied
Trumac Healthcare offers 1 brand option for Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet — each available in different pack sizes with trade-friendly margins. View the brand-specific pages below for detailed specifications, MRPs and packaging options.
For PCD franchise opportunities, monopoly distribution rights, or third-party contract manufacturing of Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet, contact our business development team. WhatsApp +91 9041677932 or email info@trumachealthcare.net.
Frequently Asked Questions
Who is the manufacturer of Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet?
Trumac Healthcare is a WHO-GMP certified manufacturer of Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet in India. We supply our own brand range (see brand options above) and also offer third-party contract manufacturing for PCD distributors.
Is Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet available for PCD pharma franchise on monopoly basis?
Yes. We offer Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet for PCD/Propaganda-cum-Distribution pharma franchise on monopoly basis across all districts of India. Contact our business development team for pricing and territory availability.
What pack sizes are available for Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet?
Available pack sizes include: 10 x 10 (Alu Alu).
What is the MRP / trade price for Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet?
MRPs range from ₹1100 to ₹1100 across our brand variants. Trade-friendly PTR/PTS margins available on request — WhatsApp +91 9041677932 for current rates.
How do I place an order or franchise enquiry?
WhatsApp +91 9041677932 or email info@trumachealthcare.net with your enquiry. Our team will revert within 24 hours with full pricing, brochure and franchise terms.
Ready to start your PCD franchise for Isosorbide Dinitrate 20 mg + Hydralazine 37.5 mg Tablet?