Brivamac-100 Tablet
Brivaracetam 100 mg Tablets — High-Strength Third-Generation Antiepileptic
| Composition | Brivaracetam 100 mg |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10 Tablets |
| MRP | ₹ 4950 |
| Therapy | Neurology — Third-Generation Antiepileptic (SV2A Modulator) |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Brivamac-100 Tablet
Brivamac-100 Tablet contains Brivaracetam 100 mg — the higher-strength variant for patients requiring full therapeutic dosing. The 100 mg twice-daily dose is the upper-end maintenance dose for refractory focal epilepsy or for patients who have inadequate seizure control on Brivamac-50.
Brivaracetam offers significant advantages over older antiepileptics: faster onset of efficacy (often within days), no titration required to start or stop, fewer drug-drug interactions than enzyme-inducing antiepileptics, and significantly lower behavioural side effects than Levetiracetam. Its selective SV2A binding mechanism gives it a clean tolerability profile.
Brivamac-100 is manufactured by Trumac Healthcare under WHO-GMP conditions. Available for monopoly-based PCD pharma franchise and third-party manufacturing — a premium specialty neurology SKU.
Indications
- Refractory focal-onset seizures requiring upper therapeutic dosing
- Adjunctive therapy in patients inadequately controlled on Brivamac-50
- Monotherapy in established focal epilepsy
- Conversion therapy from Levetiracetam
Mechanism of Action
Selective high-affinity SV2A ligand action modulates neurotransmitter release in epileptic neurons, reducing abnormal hypersynchronous firing. The 100 mg twice-daily dose achieves higher SV2A receptor occupancy for refractory seizure control.
Dosage & Administration
Adults: 100 mg twice daily, may be adjusted up to a maximum of 200 mg/day total. Dose adjustment in hepatic impairment. May be taken with or without food. Can be started or stopped without titration.
Side Effects
Drowsiness, dizziness, fatigue, headache, nausea. Less common: behavioural disturbances, bronchospasm, angioedema.
Contraindications & Precautions
Hypersensitivity to brivaracetam, levetiracetam or pyrrolidone derivatives. Caution in hepatic impairment, psychiatric history, sedating medications. Pregnancy — only if essential.
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Brivamac-100 Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Brivamac-100 Tablet used for?
Brivamac-100 contains Brivaracetam 100 mg and is used for refractory focal-onset seizures in adults requiring upper-end therapeutic dosing.
When should the 100 mg dose be used?
After establishing partial response on Brivamac-50, or in patients with refractory focal epilepsy requiring upper therapeutic dosing — under specialist supervision.
Is Brivamac-100 available for PCD pharma franchise?
Yes, Trumac Healthcare offers Brivamac-100 Tablet on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Brivamac-100 Tablet be stored?
Store below 30 °C in a dry place, away from direct sunlight and moisture.
Is Brivamac-100 WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
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