Gabacam-NT 400 Tablet
Gabapentin 400 mg + Nortriptyline 10 mg Tablets — High-Strength Combination
| Composition | Gabapentin 400 mg + Nortriptyline 10 mg |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10 Tablets |
| MRP | ₹ 1650 |
| Therapy | Neuro / G.P. — Gabapentinoid + Tricyclic (High Dose) |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Gabacam-NT 400 Tablet
Gabacam-NT 400 is the high-dose combination — Gabapentin 400 mg + Nortriptyline 10 mg — for refractory neuropathic pain where 300 mg dose is inadequate. Total daily Gabapentin reaches 1200–2400 mg.
Manufactured by Trumac Healthcare under WHO-GMP. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Refractory diabetic neuropathy
- Severe post-herpetic neuralgia
- CIPN refractory to lower doses
- Chronic widespread pain syndromes
Mechanism of Action
Gabapentin is a structural analogue of GABA that binds the alpha-2-delta subunit of voltage-gated calcium channels in CNS, reducing release of excitatory neurotransmitters (glutamate, noradrenaline, substance P). This dampens hyperexcitability in neurons responsible for neuropathic pain and partial seizures. Nortriptyline is a tricyclic antidepressant that inhibits reuptake of noradrenaline and serotonin in CNS — augmenting descending inhibitory pain pathways. Combined with Gabapentin, it addresses both spontaneous and evoked components of neuropathic pain.
Dosage & Administration
Adults: 1 tablet twice daily; may up-titrate to three times daily.
Side Effects
Dizziness, somnolence, peripheral oedema, weight gain, ataxia, blurred vision. Generally well tolerated; sedation dose-dependent. Anticholinergic effects. Higher sedation than lower strengths.
Contraindications & Precautions
Hypersensitivity. Caution in renal impairment (dose adjust). Avoid abrupt discontinuation. Caution in elderly and history of substance abuse.
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Gabacam-NT 400 Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Gabacam-NT 400 Tablet used for?
Gabacam-NT 400 Tablet contains Gabapentin 400 mg + Nortriptyline 10 mg. Used as per the indications described above.
How should Gabacam-NT 400 Tablet be taken?
As directed by your physician. Complete the prescribed course.
Is Gabacam-NT 400 Tablet available for PCD pharma franchise?
Yes, Trumac Healthcare offers Gabacam-NT 400 Tablet on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Gabacam-NT 400 Tablet be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Gabacam-NT 400 Tablet WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
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