Glucim-V 1/0.2 SR Tablet
Glimepiride 1 mg + Metformin 500 mg + Voglibose 0.2 mg (SR)
| Composition | Glimepiride 1 mg + Metformin 500 mg + Voglibose 0.2 mg (SR) |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Box |
| Pack Size | 10 x 15 (Blister) |
| MRP | ₹ 1650 |
| Therapy | Cardiac + Diabetic — Sulphonylurea + biguanide + alpha-glucosidase inhibitor (Triple OAD SR) |
| Storage | Store below 25°C. |
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About Glucim-V 1/0.2 SR Tablet
Glucim-V 1/0.2 SR Tablet contains Glimepiride 1 mg + Metformin 500 mg + Voglibose 0.2 mg (SR). The combination provides three complementary mechanisms: Glimepiride stimulates insulin secretion, Metformin reduces hepatic glucose output, and Voglibose delays intestinal carbohydrate digestion to flatten the post-prandial glucose peak.
It is particularly suited to patients with type-2 diabetes showing prominent post-prandial hyperglycaemia despite dual oral therapy.
Camrut Healthcare manufactures the Glucim-V range under WHO-GMP conditions for PCD pharma franchise across India.
Indications
- Type-2 DM with prominent post-prandial hyperglycaemia
- Inadequate control on Glimepiride + Metformin combination
- Patients with high carbohydrate intake patterns
Mechanism of Action
Glimepiride closes pancreatic K-ATP channels, triggering insulin secretion. Metformin activates AMPK, suppressing hepatic glucose output. Voglibose is an alpha-glucosidase inhibitor in the small-intestinal brush border, delaying breakdown of disaccharides and oligosaccharides — flattening the post-prandial glucose rise.
Dosage & Administration
['Adults: 1 tablet at the start of breakfast', 'Voglibose must be taken with the first bite of food', 'Swallow whole', 'Monitor HbA1c and post-prandial glucose']
Side Effects
['Hypoglycaemia', 'GI flatulence and abdominal distension (voglibose)', 'GI upset (metformin)', 'Hypoglycaemia recovery requires glucose, not sucrose']
Contraindications & Precautions
['Type-1 diabetes', 'Severe renal impairment', 'Severe hepatic impairment', 'Inflammatory bowel disease', 'Pregnancy and breastfeeding']
Storage
Store below 25°C.
Glucim-V 1/0.2 SR Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
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