Metcam-500 SR Tablet
Metformin 500 mg SR
| Composition | Metformin 500 mg SR |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Box |
| Pack Size | 10 x 10 |
| MRP | ₹ 339.3 |
| Therapy | Cardiac + Diabetic — Biguanide (Sustained Release) |
| Storage | Store below 25°C. |
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About Metcam-500 SR Tablet
Metcam-500 SR Tablet contains Metformin 500 mg SR in sustained-release formulation. Metformin is the first-line oral antidiabetic agent for type-2 diabetes recommended by ADA, EASD and ICMR guidelines. The SR formulation improves GI tolerability and provides smoother 24-hour glucose control.
Indicated as monotherapy or in combination with other oral antidiabetics or insulin for adult type-2 diabetes mellitus. Also used in prediabetes, PCOS and gestational diabetes (some forms).
Camrut Healthcare manufactures the Metcam range under WHO-GMP conditions for PCD pharma franchise across India.
Indications
- Type-2 diabetes mellitus (first-line)
- Prediabetes (impaired fasting glucose or impaired glucose tolerance)
- PCOS with insulin resistance
- Gestational diabetes (under obstetrician supervision)
Mechanism of Action
Metformin is a biguanide that activates AMP-activated protein kinase (AMPK), suppressing hepatic gluconeogenesis (the predominant mechanism), improving peripheral insulin sensitivity and reducing intestinal glucose absorption. Unlike sulphonylureas, metformin does not cause hypoglycaemia and is weight-neutral or modestly weight-reducing.
Dosage & Administration
['Adults: 1 tablet once or twice daily with meals', 'Swallow whole', 'Start at lower dose and titrate up', 'Monitor renal function annually']
Side Effects
['GI upset, diarrhoea (most common, dose-related)', 'Metallic taste', 'Vitamin B12 deficiency (chronic use)', 'Lactic acidosis (very rare; avoid in renal impairment)']
Contraindications & Precautions
['eGFR < 30 mL/min/1.73 m²', 'Severe hepatic impairment', 'Acute or chronic metabolic acidosis', 'Acute heart failure', 'Severe dehydration']
Storage
Store below 25°C.
Metcam-500 SR Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
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