Cefiza-100 DT Tablet
Cefixime Trihydrate 100 mg Dispersible Tablets — Third-Generation Cephalosporin
| Composition | Cefixime Trihydrate 100 mg |
|---|---|
| Dosage Form | Dispersible Tablet |
| Pack Type | Strip |
| Pack Size | 10 x 10 Tablets |
| MRP | ₹ 950 |
| Therapy | Antibiotic + G.P. + Orthopaedics — Third-Generation Cephalosporin |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Cefiza-100 DT Tablet
Cefiza-100 DT Tablet contains Cefixime 100 mg in a dispersible tablet format. Cefixime is a third-generation oral cephalosporin with broad-spectrum activity against gram-negative bacteria including Enterobacteriaceae, Haemophilus influenzae, Moraxella catarrhalis and Neisseria species. The DT format dissolves rapidly in water — suited to older children, adolescents and adults with swallowing difficulty.
Cefixime is the most widely used third-generation oral cephalosporin in Indian practice for community-acquired infections. Its once or twice daily dosing, oral bioavailability and broad gram-negative coverage make it valuable for UTI, gonorrhoea, typhoid fever, ENT infections and acute exacerbations of chronic bronchitis.
Cefiza-100 DT Tablet is manufactured by Trumac Healthcare under WHO-GMP conditions. Available for monopoly-based PCD pharma franchise and third-party manufacturing — one of the highest-volume cephalosporin SKUs.
Indications
- Acute pharyngitis and tonsillitis (streptococcal)
- Acute otitis media
- Acute exacerbations of chronic bronchitis
- Uncomplicated UTI and cystitis
- Uncomplicated gonorrhoea (single dose)
- Typhoid fever (uncomplicated)
Mechanism of Action
Cefixime binds penicillin-binding proteins (PBP-3) on gram-negative bacteria, inhibiting the final transpeptidation step of peptidoglycan synthesis. The result is bacterial cell wall destabilisation and osmotic lysis. Cefixime is resistant to many beta-lactamases produced by gram-negative organisms — distinguishing it from earlier cephalosporins.
Dosage & Administration
Adults: 200–400 mg/day in one or two divided doses for 5–7 days. Children: 8 mg/kg/day. Disperse in water and drink the suspension.
Side Effects
Diarrhoea (relatively common), nausea, abdominal pain, mild skin rash. Less common: hypersensitivity reactions, transient elevation of liver enzymes. Rare: pseudomembranous colitis, severe skin reactions, anaphylaxis.
Contraindications & Precautions
Hypersensitivity to cephalosporins. Severe penicillin allergy (cross-reactivity ~10%). Renal impairment requires dose adjustment. History of GI disease (caution).
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Cefiza-100 DT Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Cefiza-100 DT used for?
Cefiza-100 DT contains Cefixime 100 mg dispersible and is used for bacterial infections — UTI, ENT, respiratory tract, gastrointestinal and gynaecological infections in the appropriate age group.
How long is the course?
Typical course is 5–7 days; longer in complicated infections. Always complete the prescribed course to prevent resistance.
Is Cefiza-100 DT available for PCD pharma franchise?
Yes, Trumac Healthcare offers Cefiza-100 DT on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Cefiza-100 DT be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Cefiza-100 DT WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
Related Products
- Cefiza Drops — Cefixime 25 mg / ml
- Cefiza-200 DT Tablet — Cefixime Trihydrate 200 mg (Dispersible)
- Cefiza-100 Dry Syrup — Cefixime 100 mg / 5 ml (Dry Syrup with Water)